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"While the averages are what they are, I am still not pleased. First, how is it that we have Mosley and Cotto but no Antonio Margarito? I'm not lobbying for the Tijuana Tornado (a/k/a "Hands of Plaster"), but come on. Mosley has been on hiatus for as long as Margarito's suspension and may well still be when Margarito returns.

Nobody is saying that surrogate indicators should be abandoned altogether. Many well known drugs on the market today, including the breast cancer drug Gleevac (imatinib) and HIV fighting antiretrovirals, were approved based on surrogate endpoints, and scandals are rare. "You don't want to deprive the public of a drug that possibly works," says Arthur Schatzkin, chief of nutritional epidemiology at the National Cancer Institute in Bethesda, Maryland.

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Meat shouldn be kept wrapped with plastic in the fridge it makes it rot. It should be covered with cheese cloth. Asparagus should be kept in a moist cloth not plastic. It is all too often forgotten in general practice (and research) that surrogate markers are a compromise (or preliminary result) that should be further investigated (for example though outcome research). Even those who haven heard of Christian Louboutin have seen his shoes. They marked by his trademark red sole, the result of a lucky experiment with a Mary Jane and a bottle of nail polish many years ago.

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The Senate committee had already approved making (shoplouboutinaustralia.org) salary and employment histories public, and yesterday, a state House committee passed legislation that included the same provisions. Neither chamber has yet voted in full on any personnel law changes. With every passing year the popularity flat irons are gradually gaining momentum
 
 

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